Overview of the Global Organ-on-Chip Industry:

The Global Organ-on-Chip market is projected to experience substantial growth between 2024 and 2030, driven by digital transformation, innovation in service delivery, and expanding global demand. The Global Organ-on-Chip Market size was valued at around USD 126 million in 2024 and is projected to reach USD 950 million by 2030. Along with this, the market is estimated to grow at a CAGR of around 40% during the forecast period (2025-30). This report offers an in-depth analysis of the key drivers, challenges, competitive landscape, and future outlook — helping businesses, investors, and stakeholders make informed decisions.

Market Size & Forecast (2024–2030)

• Base Year: 2024
• Forecast Period: 2025–2030
• Estimated CAGR (2025–2030): 40%

Key Market Driver (What’s Driving Organ-on-Chip Sector Growth?)

Growing Demand for Alternatives to Animal Testing in Drug Discovery – The worldwide market for organ-on-chip technology is driven by the growing need for alternatives to animal testing in drug discovery. To enhance safety & efficacy evaluations and lessen the ethical issues surrounding animal testing regulatory organizations like the FDA and EMA promote the use of sophisticated in-vitro models. The FDA Modernization Act 2.0. passed by the USA government in the year 2022, will greatly decrease the use of animal drug testing by promoting the use of substitute techniques like organ-on-chips. Precise simulation of human organ function through systems such as the liver and lung on chips offers increased predictive accuracy of drug toxicity and metabolism studies. For instance; Emulate's liver on a chip has been widely utilized to predict hepatotoxicity in candidates for drugs reducing dependence on animal models. This shows how Organ-On-Chip technology is changing the scenario of preclinical testing to provide ethical and cost-effective solutions for the pharmaceutical industry with alternatives to animal testing.

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Top Companies in the Organ-on-Chip Market

Here’s a snapshot of key players leading innovation and market share:

• Altis Biosystems
• AlveoliX AG
• Axosim
• Bi/ond Solutions B.V
• Cherry Biotech
• CN-Bio
• Emulate, Inc.
• Hesperos, Inc.
• Insphero
• MesoBioTech
• Mimetas B.V.
• Nortis Inc.
• React4Life
• TARA Biosystems (Valo Health)
• TissUse GmbH
• Others

Includes SWOT analysis, revenue trends, partnerships, and product launches.

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Organ-on-Chip Market Segmentation Analysis

-By End User

• Pharmaceutical and biotechnology companies
• Cosmetics industry
• Academic and research institutes
• Others

Based on end users, pharmaceutical and biotechnology lead the market. It holds approx. 73% market share. This growth is because of their considerable use of OoC systems for drug discovery, testing of toxicity, and the modeling of diseases.

-By Organ Type

• Liver
• Intestine
• Kidney
• Lung
• Heart
• Other organs

Based on organ type, the Liver segment leads the global market. It holds approx. 30% of the total market value.

-By Model Type

• Organ-Based Model- Market Size & Forecast 2020-2030, USD Million
• Disease-Based Model- Market Size & Forecast 2020-2030, USD Million

-By Material

• Polydimethylsiloxane (PDMS)- Market Size & Forecast 2020-2030, USD Million
• Polymer- Market Size & Forecast 2020-2030, USD Million
• Glass- Market Size & Forecast 2020-2030, USD Million

-By Solution

• Products- Market Size & Forecast 2020-2030, USD Million
• Services- Market Size & Forecast 2020-2030, USD Million

-By Application

• Toxicology Research-Market Size & Forecast 2020-2030, USD Million
• Drug Discovery-Market Size & Forecast 2020-2030, USD Million
• Physiological Model Development-Market Size & Forecast 2020-2030, USD Million
• Stem cell Research-Market Size & Forecast 2020-2030, USD Million
• Tissue regeneration and regenerative Medicines-Market Size & Forecast 2020-2030, USD Million
• Others

Geographical Analysis

-By Region

• North America
• South America
• Europe
• The Middle East & Africa
• Asia-Pacific

Out of them, North America dominates the Global Organ-on-Chip Market. It holds approx. 52% market share.

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Methodology Behind the Report

This research combines qualitative and quantitative methods, including:

• Expert interviews
• Proprietary forecasting models
• Financial and trade databases
• Government and institutional data

Forecasts are validated using top-down and bottom-up approaches to ensure accuracy and reliability.

Frequently Asked Questions About the Organ-on-Chip Market

1. What is the growth rate of the Organ-on-Chip market from 2025–2030?
2. Which segment are expected to dominate market?
3. Who are the top companies and what strategies being they using?
4. What are the key risks and challenges in this industry?
5. How can businesses prepare for future trends?

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