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- 16S Ribosomal RNA Sequencing for Gut Microbiota16S Ribosomal RNA Sequencing for Gut Microbiota is a pivotal technique used to analyze and understand the complex communities of microorganisms residing in the gastrointestinal tract. This method targets the 16S rRNA gene, which is highly conserved among different species of bacteria, allowing researchers to identify and classify bacterial populations within the gut ecosystem accurately. By...0 Комментарии 0 Поделились 200 ПросмотрыВойдите, чтобы отмечать, делиться и комментировать!
- Carbohydrate Modification based Half-Life ExtensionBioactive natural protein conjugation is a cutting-edge technique that involves linking bioactive molecules to natural proteins to enhance their functionality or therapeutic potential. This process allows for the creation of multifunctional biomolecules that can perform specific tasks, such as targeted drug delivery, improved stability, or enhanced bioavailability. By utilizing bioactive...0 Комментарии 0 Поделились 184 Просмотры
- Ribosomal Defects: Genetic, Acquired, and Epigenetic SaboteursGenetic Mutations: From Anemia to Developmental Disorders RP mutations: RPS19 defects impair 18S rRNA processing, reducing functional 40S subunits and causing Diamond-Blackfan anemia (DBA). rRNA biogenesis defects: SBDS gene mutations in Shwachman-Diamond syndrome disrupt 60S subunit maturation, leading to pancreatic insufficiency and leukemia predisposition.0 Комментарии 0 Поделились 192 Просмотры
- Single Cell RNA SequencingSingle Cell RNA Sequencing (scRNA-seq) is a transformative technology that enables the analysis of gene expression at the individual cell level. This approach allows researchers to unravel the complexities of cellular heterogeneity within tissues, identifying unique cell types and revealing developmental pathways that are often masked in bulk tissue analysis. By applying Single Cell RNA...0 Комментарии 0 Поделились 246 Просмотры
- Circle-Seq based eccDNA IdentificationExtrachromosomal circular DNA (eccDNA) is a fascinating genetic element found in both normal and cancerous cells. Unlike the linear DNA typically organized within chromosomes, eccDNA exists as small, circular molecules that can carry genes or regulatory elements. Recent research has highlighted the role of eccDNA in genomic diversity, contributing to gene amplification and expression...0 Комментарии 0 Поделились 238 Просмотры
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