Changing Paradigms in Neurofibromatosis Care Neurofibromatosis constitutes a family of hereditary disorders distinguished by aberrant cellular regulation leading to multisystem benign tumor formation across neural pathways. Typical neurofibromatosis symptoms encompass distinctive pigmented lesions called café-au-lait spots, pathological freckling in axillary and inguinal regions, ocular hamartomas termed Lisch nodules, and nerve...