What is Single-Cell ATAC Sequencing (scATAC-seq)?
Single-cell ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing) is an innovative technique that enables the investigation of chromatin accessibility at the single-cell level. The accessibility of chromatin—whether it is in an open or closed configuration—critically impacts gene expression and cell fate....
EM-seq (Enzymatic Methyl-sequencing), a cutting-edge technique for identifying DNA methylation profiles, is showing great potential in various fields, including epigenetic research, disease diagnosis, and the early detection of cancer. Compared to the traditional whole-genome bisulfite sequencing (WGBS), EM-seq offers several advantages. It allows for the creation of DNA sequencing...
Principal Component Analysis (PCA) is a technology for simplified analysis of data sets. PCA uses variance decomposition to reduce the dimensionality of multi-dimensional data, remove noise and redundancy, and reveal the most important elements and structures hidden behind complex data. In the field of life sciences, in proteomics and metabolomics research applications, it is usually necessary...
Evolutionary analysis can reveal the genetic sequence relationship of classification in the evolution process from the perspective of molecular evolution. In the process of biological information analysis, phylogenetic trees are often used to present the analysis results. The phylogenetic tree can reveal the biological evolution process and mechanism of related species or genes. The...
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